Chylomicron metabolism
نویسندگان
چکیده
منابع مشابه
Chylomicron metabolism.
Chylomicrons are the 'orphans' of the lipoprotein family. Difficulty of measurement has impeded understanding of their metabolism. Plasma concentrations of chylomicrons and chylomicron remnants give no insight into the magnitude of substrate flux through these pathways. A defect in clearance of chylomicron remnants is probably an indication of a more generalized defect in lipoprotein metabolism...
متن کاملMetabolism of chylomicron proteins in the dog.
It has been amply demonstrated that the chylomicron is a particulate complex of triglyceride, cholcstcrol c&r, phospholipide, and protein (l-4) and is the form in which most of the exogenous triglyceride (5) and choltstcrol (6, 7) is transported from the intestinal tract to the tissuts via the lymph and blood. Although the m&holism of the triglyccridc moiety of the chylomicrons has been studied...
متن کاملChylomicron metabolism. Chylomicron uptake by bone marrow in different animal species.
Previously it was shown in rabbits that 20-40% of the injected dose of chylomicrons was cleared from the plasma by perisinusoidal bone marrow macrophages. The present study was undertaken to determine whether the bone marrow of other species also cleared significant amounts of chylomicrons. Canine chylomicrons, labeled in vivo with [14C]cholesterol and [3H] retinol, were injected into marmosets...
متن کاملChylomicron metabolism by the isolated perfused mouse heart.
The catabolism of rat chylomicrons, labeled in their triacylglycerol (TG) component, was investigated using perfused working mouse hearts. Perfusion of mouse hearts with heparin increased lipoprotein lipase (LPL) activity in the perfusate. This heparin-releasable LPL pool remained constant over a variety of experimental conditions, including workload and fatty acid concentrations, making the mo...
متن کاملThe role of unesterified fatty acid transport in chylomicron metabolism.
In a study to determine the early fate of absorbed fat, previously reported from this laboratory, observations were made on the removal of chylomicra containing triglyceride labeled with palmitic acid-l-C14 from the plasma of the anesthetized dog (1). It was found that the triglyceride fatty acids (TGFA) rapidly appeared in the albumin-bound unesterified fatty acid fraction (UFA) of the plasma....
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1989
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(19)84662-8